Past Symposia
The CRED organized an outstanding symposium held in conjunction with the 59th Annual NIEHS Center Directors Meeting in Austin in 2001, entitled “Environmental Carcinogenesis: Hormones, Xenobiotics and Chemoprevention”. There were also symposia in both 2003 and 2004 entitled, respectively, “Experimental Models of Human Disease” and “Diet, Obesity, Physical Activity and Cancer”. Generally, these symposia involved a mix of speakers both from outside the CRED as well as from within the Center and have been very well attended. The symposia are outlined below.
“Environmental Carcinogenesis: Hormones, Xenobiotics and Chemoprevention”
October 21, 2001 (held in conjunction with the 59th Annual NIEHS Center Directors Meeting)
Morning Session:
Chair: Melissa Bondy, Ph.D. (UTMDACC Houston)
David Moore, Ph.D. (Baylor College
of Medicine) - Regulation of Drug Metabolism by the Xenobiotic Receptor
CAR
Stephen
Safe, Ph.D. (Texas A&M University) - A new Mechanism of Estrogen
Action in Breast Cancer
Judy Bolton, Ph.D. (University of Illinois at Chicago)
Equine Estrogen Quinone Induced DNA Damage: Alkylation Versus Oxidation
Cheryl
Walker, Ph.D. (UTMDACC, SPRD) - A Functional Genomics Approach to Understanding
the Tissue-specific Activity of SERMs
Marcelo Aldaz, M.D., Ph.D. (UTMDACC,
SPRD) - Global Gene Expression Studies in Breast Cancer
Claudio Conti, Ph.D.
(UTMCADD, SPRD) - Prostate Carcinogenesis in IGF-1 Transgenic Mice
Afternoon Session:
Chair: Susan Fischer, Ph.D. (UTMDACC, SPRD)
Raymond DuBois, M.D., Ph.D. (Vanderbilt
University) - NSAIDs, COXIBs and Colon Cancer Prevention
Scott Lippman, M.D.
(UTMDACC) - Cancer Chemoprevention: Progress and Promise
Maarten Bosland,
D.V.Sc., Ph.D. (New York University School of Medicine) - Prostate Cancer
Chemoprevention
Leonard Bjeldanes, Ph.D. (University of California, Berkeley)
- Cancer Protective Cellular Effects of Dietary Indoles
Chung S. Yang, Ph.D.
(Rutgers University) - Inhibition of Carcinogenesis by Tea
George Bailey,
Ph.D. (Oregon State University) - Chlorophyllin Cancer Chemoprevention:
Quantitative Intervention in the Rainbow Trout Model
John Groopman, Ph.D.
(Johns Hopkins University) - Clinical Chemoprevention Trials in China: Modulation
of Biomarkers “Experimental Models of Human Disease”
Experimental Models of Human Disease
May 5, 2003
Keynote Speaker: Martine Roussel (St. Jude Research Hospital) - Cyclin-Dependent Kinase Inhibitors in Development and Cancer
Morning Session: Cell Cycle
Chair: John Richburg (UT Austin)
Rodney Nairn (UTMDACC, SPRD) - Genetics
of Melanoma Susceptibility in Xiphophorus Hybrids
Beverly Mock (NCI) - The
Genetics of Susceptibility to Mouse Plasmacytomagenesis
Claudio Conti (UTMDACC,
SPRD) - D-Cyclins, CDKs and Cancer: Lessons from Animal Models
David Johnson
(UTMDACC, SPRD) - Tumor Suppression by the E2F1 Transcription Factor
Afternoon Session: P53 and DNA Damage
Chair: Gerry Adair, Ph.D (UTMDACC, SPRD)
Gigi Lozano (UTMDACC) - Mouse Models
Unravel p53 Functions
Larry Donehower (Baylor College of Medicine) - Cancer
and Aging Phenotypes in p53 Mutant Mice
Jan Vijg (University of Texas Health
Science Center of San Antonio) - Accelerated Aging in Mouse Models of DNA
Repair Defects
Karen Vasquez (UTMDACC, SPRD) - Triplex DNA as a Tool for Studying
DNA Repair in Animal Models
May 6, 2003
Morning Session: Signaling
Chair: Terry Monks (UT Austin)
Mark Bedford (UTMDACC, SPRD) - A Functional
Analysis of the Arginine Methyltransferase - CARM1
Cheryl Walker (UTMDACC,
SPRD) - The Road Less Traveled: Finding Points of Convergence Between the
Etiology of Human and Animal Tumors
Yinling Hu (UTMDACC, SPRD) - IKKa Maintains
Genomic Integrity Through Regulation of the G2/M Phase of the Cell Cycle
Technology
Chair: Mike MacLeod (UTMDACC, SPRD)
Bo Yuan (Ohio State University Medical
Center) - To Decipher the Book of Life - Sequence, Structure, and Function
Organization and Complexity of the Human and Mouse Genomes
Howard Jacob (Medical
College of Wisconsin) - Genetic Models for Drug Discovery and Toxicology
Tom
Doetschman (University of Cincinnati) - Interpretation of Phenotype in Genetically
Engineered Mice
Serrine Lau (UT Austin) - Mass Spectrometric Proteomics Approach
to Identify Protein Targets of Environmental Chemicals
Prevention
Chair: Melissa Bondy (UTMDACC)
Sue Fischer (UTMDACC, SPRD) - Is COX-2 a Good
Target for Skin Cancer Prevention?
Steve Hursting (NIH) - Diet-Gene Interactions
in Transgenic Mice: IGF-1 as a Molecular Target
John DiGiovanni (UTMDACC,
SPRD) - Mouse Models of Enhanced Growth Factor Signaling for Studies of Epithelial
Carcinogenesis and its Prevention
John Clifford (UTMDACC) - Chemopreventive
Action of Phenylretinamides in Skin
“Diet, Obesity, Physical Activity
and Cancer”
“Diet, Obesity, Physical Activity and Cancer”
May 3, 2004
Keynote Speaker: Michael J. Thun (American Cancer Society) - Overview/Perspective on the Relationship Between Diet, Obesity and Cancer
Morning Session:
Obesity/Calorie Restriction
Chair: Steve Hursting (NCI)
Soren Snitker (University of Maryland) - Obesity
and Cancer
Sara Strom (UTMDACC) - Obesity as a Factor for Late Stage Disease
Margo Cleary
(University of Minnesota) - Animal Model: Obesity and Mammary Cancer
Rajana
Bird (University of Waterloo) - Energy Restriction and the Multistep Process
of Colon Carcinogenesis
Stephen D. Hursting (NCI) - Calories and Cancer: Mechanistic
Approaches with a Focus on IGF-1
Afternoon Session:
Physical Activity and Exercise
Chair: Henry J. Thompson (Colorado State University)
Molly Bray (University
of Texas School of Public Health) - Human Physical Exercise
Christine Friedenreich
(Alberta Cancer Board) - Review of the Epidemiologic Evidence on the Association
Between Physical Activity and Cancer Risk
Henry Thompson (Colorado State
University) - The Effect of Exercise on Mammary Carcinogenesis
May 4, 2004
Morning Sessions: Dietary Factors
Chair: Clement Ip (Roswell Park Cancer Institute)
Anita L. Sabichi (UTMDACC)
- The SELECT Trial: Prostate Cancer Chemoprevention with Selenium and Vitamin
E
Xifeng Wu (UTMDACC) - Bladder Cancer
Russell D. Klein (The Ohio State University)
- Rethinking the Link between Dietary Fat and Prostate Cancer
Future Directions/Public Education
Chair: Melissa Bondy (UTMDACC)
Allen Dearry (NIEHS) - NIEHS Plans to Address
Obesity and the Environment
Linda Nebeling (NCI) - NCI's Transdisciplinary
Energy Balance Initiative
Robin Fuchs-Young (UTMDACC, SPRD) - Practical
Prevention: Translating Scientific Results into Usable Information for the
Public
Conferences
The CRED was co-sponsor for the following conferences:
- Gulf Coast Chapter SOT (2000 – Austin, TX)
- American Association for Cancer Research Meeting on Molecular and Genetic Epidemiology of Cancer (2003 – Honolulu, HI)
- Third International Experimental Skin Carcinogenesis Conference (1998 – Bastrop, TX)
- Fourth International Experimental Skin Carcinogenesis Conference (2000 – Tuscon, AZ)
- Fifth International Experimental Skin Carcinogenesis Conference (2002 – Gifu, Japan)
- Montagna Symposium on the Biology of Skin and Sixth International Experimental Skin Carcinogenesis Conference (2004 – Salishan, OR)
